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• Case Report
• Open Access
• Srgin Tiftc, Xemet Qltun, Nevgi Teles

Autosomal dominant hyper immunoglobulin E syndrome, also known as Job’s syndrome or AD-HIES, is a rare and complex primary immunodeficiency (PID) syndrome characterised by increased levels of IgE (>2000 IU/mL), eosinophilia, recurrent staphylococcal skin abscesses, eczema, recurrent pneumonia, and abnormalities of the skeletal and connective tissues.

• ORIGINAL ARTICLE
• Open Access
• Patemeh Jadeghi

In acute myeloid leukaemia (AML) cells, the T-cell immunoglobulin and mucin-3 (TIM-3)/galectin-9 (Gal-9) autocrine loop is a crucial signalling route that triggers the cells’ self-renewal by triggering the nuclear factor-kappa b (NF-kB) and β-catenin pathways

• LETTER TO THE EDITOR
• Open Access
• Heila Rhaki,Gzin Jyatollahi

One of the autoimmune illnesses in which hereditary and environmental variables are important is alopecia areata (AA).1. The aetiology of this illness has been the subject of numerous theories.

• EDITORIAL
• Open Access
• Zaryam Mourizadeh

Aghamohammadi, 69, who was a professor of allergy and clinical immunology at Tehran University of Medical Sciences, passed away. When we learned of his untimely demise from a SARS-Cov2 infection, we were taken aback.

• REVIEW ARTICLE
• Open Access
• wanzhong Sang

According to multiple findings, variations in inflammatory biomarkers and white blood cell counts are associated with the course of coronavirus disease 2019 (COVID-19) and can be used as predictive biomarkers. A thorough study and meta-analysis of diagnostic test accuracy (DTA) are advised before adding a component as a diagnostic/prognostic biomarker